Colon Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colon Cancer, including details on causes, treatment, symptoms.

Diagnosis and management of peritoneal carcinomatosis arising from adenocarcinoma of the colon and rectum.

Royal RE, Pingpank JF

Surgical Metabolism Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Peritoneal carcinomatosis (the implantation of tumor cells throughout the peritoneal cavity) occurs in as many as 50% of patients with colorectal cancer and in up to 25% is the only site of recurrence. There is increasing evidence that aggressive debulking of peritoneal only disease followed by intraperitoneal chemotherapy can have significant impact on the patient's quality and sometimes quantity of life. This chapter will provide an overview of the biologic basis of pathogenesis and the treatment of peritoneal metastases from colorectal cancer.

Published 8 April 2008 in Semin Oncol, 35(2): 183-91.
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