Colon Cancer Research - Causes, Treatment, Symptoms

Colon Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colon Cancer, including details on causes, treatment, symptoms.


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Volume 2 (2005), Issue 7 (July)

  1. Endoscopic management of familial colonic neoplasia.
    Gastrointest Endosc Clin N Am, 15(3): 549-80, ix-x. [Abstract] [Full-text]
  2. The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax.
    FEBS Lett, 579(17): 3695-700. [Abstract] [Full-text]
  3. Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation.
    FEBS Lett, 579(17): 3497-502. [Abstract] [Full-text]
  4. Tribromomethane exposure and dietary folate deficiency in the formation of aberrant crypt foci in the colons of F344/N rats.
    Food Chem Toxicol, 43(9): 1405-12. [Abstract] [Full-text]
  5. Kinase substrate protein microarray analysis of human colon cancer and hepatic metastasis.
    Clin Chim Acta, 357(2): 180-3. [Abstract] [Full-text]
  6. Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
    Cancer Res, 65(13): 5917-24. [Abstract] [Full-text]
  7. Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner.
    Cancer Res, 65(13): 5864-71. [Abstract] [Full-text]
  8. Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and ErbB2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis.
    Cancer Res, 65(13): 5848-56. [Abstract] [Full-text]
  9. CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity.
    Cancer Res, 65(13): 5812-7. [Abstract] [Full-text]
  10. Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers.
    Cancer Res, 65(13): 5740-9. [Abstract] [Full-text]
  11. Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation.
    Cancer Res, 65(13): 5498-505. [Abstract] [Full-text]
  12. Persistence of medical change at implementation of clinical guidelines on medical practice: a controlled study in a cancer network.
    J Clin Oncol, 23(19): 4414-23. [Abstract] [Full-text]
  13. Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial.
    Lancet Oncol, 6(7): 477-84. [Abstract] [Full-text]
  14. Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer.
    Proteomics, 5(10): 2587-601. [Abstract] [Full-text]
  15. Cytokeratin 20-positive large cell neuroendocrine carcinoma of the colon.
    Pathol Int, 55(8): 524-9. [Abstract] [Full-text]
  16. Exposure to the electrofusion process can increase the immunogenicity of human cells.
    Cancer Immunol Immunother, 54(9): 880-90. [Abstract] [Full-text]
  17. Relationship between plasma exposure of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite and antitumor response in mice bearing human colon carcinoma xenografts.
    Clin Cancer Res, 11(13): 4867-74. [Abstract] [Full-text]
  18. A homozygous mutation in MSH6 causes Turcot syndrome.
    Clin Cancer Res, 11(13): 4689-93. [Abstract] [Full-text]
  19. Furanoid sugar amino acids as dipeptide mimics in design of analogs of vasoactive intestinal peptide receptor binding inhibitor.
    J Pept Res, 66(2): 75-84. [Abstract] [Full-text]
  20. Inguinal canal as an anatomic sanctuary site of relapse in peritoneal carcinomatosis previously treated with intraperitoneal chemotherapy.
    J Surg Oncol, 91(1): 73-6. [Abstract] [Full-text]
  21. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer.
    J Clin Invest, 115(7): 1765-76. [Abstract] [Full-text]
  22. Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer.
    J Biol Chem, 280(28): 26565-72. [Abstract] [Full-text]
  23. Leptin stimulates the proliferation of human colon cancer cells in vitro but does not promote the growth of colon cancer xenografts in nude mice or intestinal tumorigenesis in Apc(Min/+) mice.
    Gut, 54(8): 1136-45. [Abstract] [Full-text]
  24. The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.
    Endocrinology, 146(8): 3235-43. [Abstract] [Full-text]
  25. NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer.
    Gut, 54(8): 1129-35. [Abstract] [Full-text]
  26. Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells.
    Cancer Immunol Immunother, 54(8): 781-91. [Abstract] [Full-text]
  27. Isolated crypts form spheres prior to full intestinal differentiation when grown as xenografts: an in vivo model for the study of intestinal differentiation and crypt neogenesis, and for the abnormal crypt architecture of juvenile polyposis coli.
    J Pathol, 206(4): 395-401. [Abstract] [Full-text]
  28. Syndrome of duodenal compression by the superior mesenteric artery following restorative proctocolectomy: a case report and review of literature.
    Sao Paulo Med J, 123(3): 151-3. [Abstract] [Full-text]
  29. Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer.
    Clin Chim Acta, 358(1): 60-7. [Abstract] [Full-text]
  30. 17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.
    Biochem Pharmacol, 70(4): 580-9. [Abstract] [Full-text]
  31. Surgical resection of primary tumors in patients who present with stage IV colorectal cancer: an analysis of surveillance, epidemiology, and end results data, 1988 to 2000.
    Ann Surg Oncol, 12(8): 637-45. [Abstract] [Full-text]
  32. Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways.
    Food Chem Toxicol, 43(10): 1483-95. [Abstract] [Full-text]
  33. Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
    Cancer Res, 65(14): 6380-7. [Abstract] [Full-text]
  34. Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers.
    Cancer Res, 65(14): 6063-9. [Abstract] [Full-text]
  35. Dual induction of apoptosis and senescence in cancer cells by Chk2 activation: checkpoint activation as a strategy against cancer.
    Cancer Res, 65(14): 6017-21. [Abstract] [Full-text]
  36. Quality control issues in the management of colon cancer patients.
    Eur J Surg Oncol, 31(6): 616-29. [Abstract] [Full-text]
  37. Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins.
    Mol Pharmacol, 68(2): 317-29. [Abstract] [Full-text]
  38. Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice.
    Int J Cancer, 116(4): 495-9. [Abstract] [Full-text]
  39. The prevalence of PIK3CA mutations in gastric and colon cancer.
    Eur J Cancer, 41(11): 1649-54. [Abstract] [Full-text]
  40. Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells.
    J Biol Chem, 280(29): 27383-92. [Abstract] [Full-text]
  41. Spectral markers in preneoplastic intestinal mucosa: an accurate predictor of tumor risk in the MIN mouse.
    Cancer Epidemiol Biomarkers Prev, 14(7): 1639-45. [Abstract] [Full-text]
  42. Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancer.
    Cancer Epidemiol Biomarkers Prev, 14(7): 1626-32. [Abstract] [Full-text]
  43. Fruits, vegetables, and hMLH1 protein-deficient and -proficient colon cancer: The Netherlands cohort study.
    Cancer Epidemiol Biomarkers Prev, 14(7): 1619-25. [Abstract] [Full-text]
  44. Sulindac inhibits beta-catenin expression in normal-appearing colon of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis patients.
    Cancer Epidemiol Biomarkers Prev, 14(7): 1608-12. [Abstract] [Full-text]
  45. Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer.
    J Lipid Res, 46(8): 1596-603. [Abstract] [Full-text]
  46. Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity.
    Clin Cancer Res, 11(14): 5248-56. [Abstract] [Full-text]
  47. Intensity of tumor budding and its prognostic implications in invasive colon carcinoma.
    Dis Colon Rectum, 48(8): 1597-602. [Abstract] [Full-text]
  48. Histologic risk factors and clinical outcome in colorectal malignant polyp: a pooled-data analysis.
    Dis Colon Rectum, 48(8): 1588-96. [Abstract] [Full-text]
  49. Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: a search for a uniform approach to a troubling disease.
    Dis Colon Rectum, 48(8): 1528-34. [Abstract] [Full-text]
  50. Novel therapeutics in colorectal cancer.
    Dis Colon Rectum, 48(8): 1632-50. [Abstract] [Full-text]
  51. Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).
    Carcinogenesis, 26(8): 1450-6. [Abstract] [Full-text]
  52. Associations between apoE genotype and colon and rectal cancer.
    Carcinogenesis, 26(8): 1422-9. [Abstract] [Full-text]
  53. Number versus distribution in classifying regional lymph node metastases from colon cancer.
    J Am Coll Surg, 201(2): 217-22. [Abstract] [Full-text]
  54. Hepatic arterial infusion of floxuridine and dexamethasone plus high-dose Mitomycin C for patients with unresectable hepatic metastases from colorectal carcinoma.
    J Surg Oncol, 91(2): 97-101. [Abstract] [Full-text]
  55. Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells.
    Mol Carcinog, 43(4): 207-14. [Abstract] [Full-text]
  56. Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARgamma in human colon cancer Caco-2 cells.
    Prostaglandins Leukot Essent Fatty Acids, 73(2): 113-9. [Abstract] [Full-text]
  57. Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation.
    Biochem Soc Trans, 33: 694-7. [Abstract] [Full-text]
  58. Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition.
    Biochem Soc Trans, 33: 689-93. [Abstract] [Full-text]
  59. Epigenetic events in the colorectum and in colon cancer.
    Biochem Soc Trans, 33: 684-8. [Abstract] [Full-text]
  60. MutYH (MYH) and colorectal cancer.
    Biochem Soc Trans, 33: 679-83. [Abstract] [Full-text]
  61. Studying the consequences of immediate loss of gene function in the intestine: APC.
    Biochem Soc Trans, 33: 665-6. [Abstract] [Full-text]
  62. Mutual paracrine effects of colorectal tumour cells and stromal cells: modulation of tumour and stromal cell differentiation and extracellular matrix component production in culture.
    Int J Exp Pathol, 86(4): 219-29. [Abstract] [Full-text]
  63. Potent reversal of multidrug resistance by ningalins and its use in drug combinations against human colon carcinoma xenograft in nude mice.
    Cancer Chemother Pharmacol, 56(4): 379-90. [Abstract] [Full-text]
  64. Expression of apoptosis related proteins during malignant progression in chronic ulcerative colitis.
    J Clin Pathol, 58(8): 811-4. [Abstract] [Full-text]
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Colon Cancer Research Today Archive:

Volume 1 (2004)
  Issue 1 (November)
  Issue 2 (December)

Volume 2 (2005)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 3 (2006)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 4 (2007)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 5 (2008)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)



Colon Cancer Books

The Colon Cancer Survivors' Guide: Living Stronger, Longer

The Colon Cancer Survivors' Guide: Living Stronger, Longer